CBD as A Neuroprotectant

Did you know that there are more than 100 active cannabinoids in cannabis? For those of you who don’t already know, cannabidiol, commonly known as CBD, accounts for almost 40 percent of the plant’s extract. CBD is considered to be one of the most important constituents for the healing of cells.

The research on CBD is still limited, no doubt, but that doesn’t mean that CBD lacks potential. From the way things are going, it appears as if emergency practitioners of stroke and cardiac units will soon start making use of CBD and its neuroprotective effects for preventing the onset of symptoms related to the conditions.

Why Cannabis Can Be Useful In Such a Situation

It is one thing to know that cannabis can be used as a neuroprotectant, it is another to understand exactly why that is the case. Cannabis is able to directly interact with the receptors of the human body. In doing so, it is not only able to prevent diseases but inhibit inflammation as well.

While there are other drugs that can be used for this exact same purpose, there are few that can compete with cannabis in this regard. Regardless of how limited the research on cannabis might be, the fact of the matter is that the level of potency that cannabis has to offer is unmatched. On top of that, the usage of CBD in such a scenario comes with no significant side effect whatsoever.

The Neuroprotective Effects of CBD

According to research, there are various therapeutic and neuroprotective effects associated with the usage of CBD. CBD can not only serve as an antidepressant but can have anxiolytic, anti-inflammatory and immunomodulatory effects as well.

CBD and Brain Ischemia

If you don’t already know, brain ischemia is a common clinical condition. This condition is involved in a number of serious diseases and medical emergencies, including the likes of cardiac arrest, strokes and respiratory arrests.

If somebody is ever faced with this condition, it is essential to restore the flow of blood as quickly as possible. But making that happen can cause secondary damage to the ischemic area of a person, which is often referred to as an ischemia/reperfusion injury. However, the question arises: why is this the case?

Well, the reason for this lies in how the restoration of blood circulation causes oxidative-stress-induced damage, as well as inflammation, in the areas that are short of nutrients and oxygen during the period of cerebral ischemia. This was highlighted in a research carried out at Fudan University in Shanghai.

According to Dr. Sean McCormick, who is a cardiac specialist, not only does CBD have preventive uses but healing benefits as well. What this means is that the usage of CBD will not only prevent inflammatory damage but heal the existing damage also.

According to research, CBD significantly improves basal respiration, spare respiratory capacity and ATP-linked oxygen consumption rate. On top of that, it augments the consumption of glucose in OGD/R-injured neurons as well. Ultimately, this points towards the fact that CBD helps in the stimulation of glucose metabolism through the pentose-phosphate pathway. As a result, this maintains the redox balance and conserves energy in neuronal ischemia/reperfusion injuries.

CBD and Neurodegenerative Disorders

Before we can get to discuss the impact of CBD on neurodegenerative disorders, it is essential to understand exactly what neurodegenerative disorders are. Neurodegenerative disease is an umbrella term that covers a wide range of conditions. What is common in all of these conditions is the fact that they affect the neurons in the human brain, in one way or the other.

Neurons are the building blocks of the nervous system in the human body, being directly linked to a number of diseases, including Parkinson’s disease and related disorders. When it comes to the cures of neurodegenerative diseases, there are no immediate cures that can be relied upon. For instance, when you speak of Parkinson’s disease, it is a fact that no cure has been found that is capable of turning the clock 

However, when you speak of CBD, it appears as if the answer to the problem might have been found. Existing research suggests that the usage of CBD might actually be able to help the patients with Parkinson’s disease.

It is so because Parkinson’s disease is directly associated with the impairment of motor control after 60-80 percent of dopamine has been lost. On top of that, digestive imbalances play a key role in the advancement of Parkinson’s disease. In this scenario, CBD can play a key role in the management of PD for the patients, owing to how it has anti-oxidant, anti-inflammatory and neuroprotectant properties.

This is not the only way in which CBD can help the patients with Parkinson’s disease, owing to how it can be used in combination with other drugs and cannabinoids for relief. For instance, different combinations of CBD, THC and THCV do wonders for relief from the symptoms of Parkinson’s disease and uplift the quality of life of the patients.


As we all know, the research on cannabis and CBD is still in its nascent phases. From what we have however, it is safe to say that there are various neuroprotective benefits that the usage of CBD has to offer. The scenario looks promising.

It is still not known, exactly, what the usage of CBD as a neuroprotectant can achieve and to what extent it can be effective. This is the reason why it is essential for the matter to be researched further, so that concrete inferences may be drawn.

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